deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02502149

Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) Scale (Elevate)

A Randomized, Open-Label Study to Evaluate the Pharmacokinetics and Safety of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc; BIIB031) Manufactured at 15K Scale and at Different Vial Strengths in Previously Treated Subjects With Severe Hemophilia A

Sponsor: Bioverativ Therapeutics Inc.

Interventions rFVIIIFc
Updated 11 times since 2017 Last updated: Dec 16, 2020 Started: Aug 31, 2015 Primary completion: Apr 30, 2017 Completion: Jun 30, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02502149, this PHASE3 trial focuses on Severe Hemophilia A and remains completed. Sponsored by Bioverativ Therapeutics Inc., it has been updated 11 times since 2015, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshotActive Not Recruiting~Mar 2017 – ~Jul 2017 · 4 months · monthly snapshotActive Not Recruiting~Jul 2017 – ~Jan 2018 · 6 months · monthly snapshotActive Not Recruiting~Jan 2018 – ~May 2018 · 4 months · monthly snapshotCompleted~May 2018 – ~Jun 2018 · 31 days · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. May 2018 — Jun 2018 [monthly]

    Completed PHASE3

  2. Jan 2018 — May 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Jul 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE3

  4. Mar 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE3

  5. Feb 2017 — Mar 2017 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Aug 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bioverativ Therapeutics Inc.
  • Swedish Orphan Biovitrum
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .