deltatrials
Unknown PHASE2 INTERVENTIONAL 1-arm NCT02504346

AZD9291, an Irreversible EGFR-TKI, in Relapsed EGFR-mutated Non-small Cell Lung Cancer Patients Previously Treated With an EGFR-TKI, Coupled to Extensive Translational Studies (TREM)

Sponsor: AstraZeneca

Interventions AZD9291
Updated 13 times since 2017 Last updated: Mar 27, 2023 Started: Aug 31, 2015 Primary completion: Jun 1, 2023 Completion: Jun 30, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Lung Cancer and Targeted Therapy and is currently ongoing. AstraZeneca leads this study, which shows 13 recorded versions since 2015 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Apr 2019 · 5 months · monthly snapshot~Apr 2019 – ~Apr 2020 · 12 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 15 months · monthly snapshot

Change History

13 versions recorded
  1. Apr 2025 — Present [monthly]

    Unknown PHASE2

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: Unknown StatusActive Not Recruiting

  5. Apr 2022 — Apr 2023 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

Show 8 earlier versions
  1. Jan 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

  2. Apr 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Apr 2019 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Nov 2018 — Apr 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  6. Jul 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  7. Feb 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Aug 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Oslo University Hospital
Data source: Oslo University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .