Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1
A Phase 1 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children With Classic 21-Hydroxylase Deficiency
Sponsor: Children's Hospital Los Angeles
Terminated
The study has been affected significantly by the COVID pandemic, drug supply/drug amendment, low recruitment interest, and FDA approval of another drug with the same indication, so this study has not met its primary endpoint data requirements.
Other terminated trials from Children's Hospital Los Angeles
Other Congenital Adrenal Hyperplasia trials with similar outcome
A PHASE1 clinical study on Congenital Adrenal Hyperplasia, this trial is terminated or withdrawn. The trial is conducted by Children's Hospital Los Angeles and has accumulated 15 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Status Flow
Change History
15 versions recorded-
Dec 2025 — Present [monthly]
Terminated PHASE1
Status: Suspended → Terminated
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Sep 2024 — Dec 2025 [monthly]
Suspended PHASE1
-
Jul 2024 — Sep 2024 [monthly]
Suspended PHASE1
-
Apr 2024 — Jul 2024 [monthly]
Suspended PHASE1
Status: Recruiting → Suspended
-
Dec 2023 — Apr 2024 [monthly]
Recruiting PHASE1
Status: Active Not Recruiting → Recruiting
▶ Show 10 earlier versions
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Mar 2023 — Dec 2023 [monthly]
Active Not Recruiting PHASE1
-
Mar 2022 — Mar 2023 [monthly]
Active Not Recruiting PHASE1
-
Mar 2021 — Mar 2022 [monthly]
Active Not Recruiting PHASE1
-
Jan 2021 — Mar 2021 [monthly]
Active Not Recruiting PHASE1
-
Apr 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE1
Status: Recruiting → Active Not Recruiting
-
Feb 2019 — Apr 2020 [monthly]
Recruiting PHASE1
-
Jun 2018 — Feb 2019 [monthly]
Recruiting PHASE1
-
Aug 2017 — Jun 2018 [monthly]
Recruiting PHASE1
Status: Not Yet Recruiting → Recruiting
-
Feb 2017 — Aug 2017 [monthly]
Not Yet Recruiting PHASE1
-
Jan 2017 — Feb 2017 [monthly]
Not Yet Recruiting PHASE1
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Children's Hospital Los Angeles
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- University of Michigan
- University of Texas Southwestern Medical Center
For direct contact, visit the study record on ClinicalTrials.gov .