deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT02581085

Tocotrienol Against the Progression of End Stage Liver Disease

Sponsor: Chandan Sen

Conditions End Stage Liver Disease NAFLD - Nonalcoholic Fatty Liver Disease NASH - Nonalcoholic Steatohepatitis
Interventions Placebo Tocotrienol (TCT)
Updated 18 times since 2017 Last updated: Feb 4, 2026 Started: Nov 1, 2019 Primary completion: Dec 16, 2026 Completion: Dec 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02581085, this PHASE2 trial focuses on End Stage Liver Disease and NAFLD - Nonalcoholic Fatty Liver Disease and remains ongoing. Sponsored by Chandan Sen, it has been updated 18 times since 2019, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2018 · 14 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Dec 2019 · 5 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Mar 2022 · 12 months · monthly snapshot~Mar 2022 – ~Mar 2023 · 12 months · monthly snapshot~Mar 2023 – ~Aug 2023 · 5 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Oct 2025 · 12 months · monthly snapshot~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

18 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Oct 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Oct 2024 — Oct 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

▶ Show 13 earlier versions

  1. Aug 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Mar 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  3. Mar 2022 — Mar 2023 [monthly]

    Recruiting PHASE2

  4. Mar 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  6. Dec 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

    Phase: None → PHASE2

  7. Jul 2019 — Dec 2019 [monthly]

    Recruiting

  8. May 2019 — Jul 2019 [monthly]

    Recruiting

  9. Feb 2019 — May 2019 [monthly]

    Recruiting

    Phase: PHASE1_PHASE2 → None

  10. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE1_PHASE2

  11. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Phase: EARLY_PHASE1 → PHASE1_PHASE2

  12. Feb 2017 — Apr 2018 [monthly]

    Recruiting EARLY_PHASE1

    Phase: PHASE2 → EARLY_PHASE1

  13. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Chandan Sen
  • Indiana University
  • Malaysia Palm Oil Board
Data source: University of Pittsburgh

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations