deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02588651

A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)

Sponsor: Deepa Jagadeesh

Conditions Adult T-cell Leukemia/Lymphoma Angioimmunoblastic T-cell Lymphoma Enteropathy Associated T-cell Lymphoma Hepato-splenic T-cell Lymphoma NK T-cell Lymphoma T-cell Lymphoma
Interventions Brentuximab vedotin
Updated 28 times since 2017 Last updated: Nov 10, 2025 Started: Jun 17, 2016 Primary completion: Oct 14, 2024 Completion: Oct 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02588651, this PHASE2 trial focuses on Adult T-cell Leukemia/Lymphoma and Angioimmunoblastic T-cell Lymphoma and remains completed. Sponsored by Deepa Jagadeesh, it has been updated 28 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2018 · 15 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Oct 2019 · 10 months · monthly snapshot~Oct 2019 – ~Mar 2020 · 5 months · monthly snapshot~Mar 2020 – ~Sep 2020 · 6 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Mar 2022 · 6 months · monthly snapshot~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Jun 2023 · 4 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Mar 2025 · 5 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Dec 2025 · 6 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

28 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE2

  2. Jun 2025 — Dec 2025 [monthly]

    Completed PHASE2

  3. Mar 2025 — Jun 2025 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  4. Oct 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  5. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

▶ Show 23 earlier versions

  1. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  2. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  3. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  4. Sep 2023 — Mar 2024 [monthly]

    Recruiting PHASE2

    Status: Active Not Recruiting → Recruiting

  5. Jul 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  6. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  7. Feb 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  8. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  9. Mar 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  10. Sep 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  11. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  12. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  14. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  15. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  16. Mar 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  17. Oct 2019 — Mar 2020 [monthly]

    Recruiting PHASE2

  18. Dec 2018 — Oct 2019 [monthly]

    Recruiting PHASE2

  19. Sep 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  20. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  21. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  22. Feb 2017 — May 2018 [monthly]

    Recruiting PHASE2

  23. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Deepa Jagadeesh
Data source: Case Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations