deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02599779

A Proof of Principle Study of Pembrolizumab With SBRT in TKI mRCC Patients (OZM-065)

A Phase II Proof of Principle Study of the Activity of Pembrolizumab (MK-3475) in Combination With SBRT in Primary Tyrosine Kinase Inhibitor (TKI) Refractory Metastatic Kidney Cancer (mRCC) Patients

Sponsor: Merck Sharp & Dohme LLC

Updated 11 times since 2017 Last updated: Aug 26, 2021 Started: Dec 31, 2016 Primary completion: Aug 31, 2021 Completion: Aug 5, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Stage IV Renal Cell Cancer AJCC V7 and is currently completed. Merck Sharp & Dohme LLC leads this study, which shows 11 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Mar 2018 · 14 months · monthly snapshotRecruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotRecruiting~Jun 2018 – ~May 2019 · 11 months · monthly snapshotRecruiting~May 2019 – ~Nov 2020 · 18 months · monthly snapshotRecruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshotRecruiting~Apr 2021 – ~Oct 2021 · 6 months · monthly snapshotRecruiting~Oct 2021 – ~Jun 2022 · 8 months · monthly snapshotCompleted~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jun 2022 — Jul 2024 [monthly]

    Completed PHASE2

  4. Oct 2021 — Jun 2022 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

  5. Apr 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

Show 6 earlier versions
  1. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  2. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  3. May 2019 — Nov 2020 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2

  5. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  6. Jan 2017 — Mar 2018 [monthly]

    Recruiting PHASE2

    First recorded

Dec 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
  • Ozmosis Research Inc.
  • Sunnybrook Health Sciences Centre
Data source: Sunnybrook Health Sciences Centre

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations