deltatrials
Completed PHASE1 INTERVENTIONAL 6-arm NCT02612662

A Study to Assess the Safety and Tolerability of Single Doses of AZD4076 in Healthy Male Subjects

A Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4076 Tetracosasodium Following Single-ascending Dose Administration to Healthy Male Subjects

Sponsor: AstraZeneca

Conditions Non-alcoholic Steatohepatitis (NASH)
Interventions AZD4076 Placebo
Updated 34 times since 2017 Last updated: Nov 18, 2025 Started: Nov 24, 2015 Primary completion: Nov 4, 2017 Completion: Oct 27, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Non-alcoholic Steatohepatitis (NASH), this trial is completed. The trial is conducted by AstraZeneca and has accumulated 34 data snapshots since 2015. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Feb 2023 · 7 months · monthly snapshot~Feb 2023 – ~Jun 2023 · 4 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~Mar 2024 · 3 months · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Dec 2025 · 6 months · monthly snapshot~Dec 2025 – present · 9 months · monthly snapshot

Change History

34 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  2. Jun 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Dec 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE1

  5. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE1

▶ Show 29 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  2. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Dec 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Sep 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1

  6. Jun 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE1

  7. Feb 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: Completed → Active Not Recruiting

  8. Jul 2022 — Feb 2023 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  9. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  10. Jan 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1

  11. Oct 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1

  12. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  13. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  14. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1

  15. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE1

  16. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  17. Jul 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE1

  18. Mar 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

  19. Dec 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE1

  20. Sep 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

  21. Jun 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

  22. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE1

  23. Feb 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE1

  24. Nov 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  25. Aug 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE1

  26. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE1

  27. Nov 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: Completed → Active Not Recruiting

  28. Feb 2017 — Nov 2017 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  29. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations