Completed PHASE1 INTERVENTIONAL 2-arm NCT02616861

Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

A 2-stage Phase 1 Study of Safety, Tolerability, PK, and PD of IW-1973 Tablet in Healthy Volunteers in an Open-label, Single-dose Stage, and a Randomized, Double Blind, Placebo-controlled, Multiple-ascending-dose Stage

Sponsor: Cyclerion Therapeutics

Conditions Healthy

Interventions IW-1973 Matching Placebo Tablet

Updated 7 times since 2017 Last updated: Apr 1, 2019 Started: Nov 30, 2015 Primary completion: May 31, 2016 Completion: Jun 30, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Healthy and is currently completed. Cyclerion Therapeutics leads this study, which shows 7 recorded versions since 2015 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
May 2019 — Jan 2021 [monthly]

Completed PHASE1
Jun 2018 — May 2019 [monthly]

Completed PHASE1

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE1
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Cyclerion Therapeutics

Data source: Cyclerion Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• San Antonio, United States