deltatrials
Terminated PHASE4 INTERVENTIONAL 2-arm NCT02623959

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

A Double Blind Randomized Controlled Trial of Indwelling Pleural Catheters Versus Indwelling Pleural Catheters Plus Doxycycline Pleurodesis for Treatment of Malignant Pleural Effusions

Sponsor: M.D. Anderson Cancer Center

Conditions Advanced Cancers Malignant Pleural Effusions
Interventions Doxycycline Fentanyl (IV) Fentanyl Patch Phone Calls Questionnaires Saline
Updated 10 times since 2017 Last updated: Jul 26, 2019 Started: Apr 27, 2016 Primary completion: May 23, 2017 Completion: May 23, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow Accrual

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This PHASE4 trial investigates Advanced Cancers and Malignant Pleural Effusions and is currently terminated or withdrawn. M.D. Anderson Cancer Center leads this study, which shows 10 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotActive Not Recruiting~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshotTerminated~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshotTerminated~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshotTerminated~Sep 2019 – ~Jan 2021 · 16 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

10 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE4

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE4

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE4

  4. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE4

  5. Sep 2019 — Jan 2021 [monthly]

    Terminated PHASE4

▶ Show 5 earlier versions

  1. Aug 2019 — Sep 2019 [monthly]

    Terminated PHASE4

    Phase: NA → PHASE4

  2. Jun 2018 — Aug 2019 [monthly]

    Terminated NA

  3. Jul 2017 — Jun 2018 [monthly]

    Terminated NA

    Status: Active Not Recruiting → Terminated

  4. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting NA

  5. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting NA

    First recorded

Apr 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • M.D. Anderson Cancer Center
Data source: M.D. Anderson Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations