deltatrials
Completed PHASE2 INTERVENTIONAL 5-arm NCT02633527

Efficacy and Safety of SPN-812 (Viloxazine Extended-release Capsule) in Children With ADHD

Evaluation of the Efficacy and Safety of SPN-812 (Viloxazine Extended-release Capsule) in Children With ADHD - A Double-Blind, Placebo-Controlled, Dose-Ranging Study

Sponsor: Supernus Pharmaceuticals, Inc.

Updated 9 times since 2017 Last updated: Sep 29, 2021 Started: Feb 1, 2016 Primary completion: Jul 25, 2016 Completion: Jul 25, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Attention-Deficit/Hyperactivity Disorder (ADHD), this trial is completed. The trial is conducted by Supernus Pharmaceuticals, Inc. and has accumulated 9 data snapshots since 2016. Psychiatric clinical trials are essential for establishing evidence-based treatment standards.

Study Description(click to expand)

This study is a randomized, double-blind, placebo-controlled, multicenter, 5-arm, parallel-group, dose-ranging study to assess the efficacy, safety, and tolerability of SPN-812 (Viloxazine Extended-release Capsule) as monotherapy in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children (6-12 years of age). Subjects are randomized in a 1:2:2:2:2 ratio to receive placebo or one of four active treatments (100 mg, 200 mg, 300 mg, or 400 mg SPN-812). The primary objective is to assess the efficacy of SPN-812 in reducing ADHD symptoms as measured by the Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition (ADHD-RS-IV).

This study is a randomized, double-blind, placebo-controlled, multicenter, 5-arm, parallel-group, dose-ranging study to assess the efficacy, safety, and tolerability of SPN-812 (Viloxazine Extended-release Capsule) as monotherapy in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children (6-12 years of age). Subjects are randomized in a 1:2:2:2:2 ratio to receive placebo or one of four active treatments (100 mg, 200 mg, 300 mg, or 400 mg SPN-812). The primary objective is to assess the efficacy of SPN-812 in reducing ADHD symptoms as measured by the Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition (ADHD-RS-IV).

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshotRecruiting~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshotCompleted~Jun 2018 – ~Sep 2020 · 27 months · monthly snapshotCompleted~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotCompleted~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshotCompleted~Nov 2021 – ~Jul 2024 · 32 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 19 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Nov 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Nov 2021 [monthly]

    Completed PHASE2

  5. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE2

Show 4 earlier versions
  1. Jun 2018 — Sep 2020 [monthly]

    Completed PHASE2

  2. Jun 2017 — Jun 2018 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

  3. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Feb 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Supernus Pharmaceuticals, Inc.
Data source: Supernus Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations