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Active Not Recruiting INTERVENTIONAL NCT02649426

A Study of the ReCor Medical Paradise System in Clinical Hypertension (RADIANCE-HTN)

The "RADIANCE-HTN" Study. A Study of the ReCor Medical Paradise System in Clinical Hypertension

Sponsor: ReCor Medical, Inc.

Updated 30 times since 2017 Last updated: Mar 31, 2026 Started: Mar 1, 2016 Primary completion: Sep 1, 2020 Completion: May 1, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Hypertension and Vascular Diseases and is currently ongoing. ReCor Medical, Inc. leads this study, which shows 30 recorded versions since 2016 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Study Description(click to expand)

Subjects with essential hypertension controlled on 1 or 2 antihypertensive medications or uncontrolled on 0-2 antihypertensive medications will be included in the RADIANCE Solo cohort while subjects with treatment resistant hypertension on a minimum of 3 antihypertensive medications will be included in the RADIANCE Trio cohort. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication (SOLO) or despite the presence of a stabilized, single pill, triple, fixed dose antihypertensive medication regimen (TRIO).

Subjects with essential hypertension controlled on 1 or 2 antihypertensive medications or uncontrolled on 0-2 antihypertensive medications will be included in the RADIANCE Solo cohort while subjects with treatment resistant hypertension on a minimum of 3 antihypertensive medications will be included in the RADIANCE Trio cohort. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication (SOLO) or despite the presence of a stabilized, single pill, triple, fixed dose antihypertensive medication regimen (TRIO).

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Jun 2017 · 3 months · monthly snapshot~Jun 2017 – ~Sep 2017 · 3 months · monthly snapshot~Sep 2017 – ~Nov 2017 · 2 months · monthly snapshot~Nov 2017 – ~Apr 2018 · 5 months · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~May 2019 · 4 months · monthly snapshot~May 2019 – ~Oct 2019 · 5 months · monthly snapshot~Oct 2019 – ~Feb 2020 · 4 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Apr 2026 · 8 months · monthly snapshotApr 21, 2026 – present · 15 days · daily API

Change History

30 versions recorded
  1. Apr 21, 2026 — Present [daily]

    Active Not Recruiting

    Phase: NANone

  2. Sep 2025 — Apr 2026 [monthly]

    Active Not Recruiting NA

  3. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

  5. Sep 2022 — Jul 2024 [monthly]

    Active Not Recruiting NA

Show 25 earlier versions
  1. Sep 2021 — Sep 2022 [monthly]

    Active Not Recruiting NA

  2. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting NA

  3. Mar 2021 — May 2021 [monthly]

    Active Not Recruiting NA

  4. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting NA

  5. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  6. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting NA

  7. May 2020 — Oct 2020 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  8. Apr 2020 — May 2020 [monthly]

    Recruiting NA

  9. Mar 2020 — Apr 2020 [monthly]

    Recruiting NA

  10. Feb 2020 — Mar 2020 [monthly]

    Recruiting NA

  11. Oct 2019 — Feb 2020 [monthly]

    Recruiting NA

  12. May 2019 — Oct 2019 [monthly]

    Recruiting NA

  13. Jan 2019 — May 2019 [monthly]

    Recruiting NA

  14. Nov 2018 — Jan 2019 [monthly]

    Recruiting NA

  15. Aug 2018 — Nov 2018 [monthly]

    Recruiting NA

  16. Jul 2018 — Aug 2018 [monthly]

    Recruiting NA

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  18. May 2018 — Jun 2018 [monthly]

    Recruiting NA

  19. Apr 2018 — May 2018 [monthly]

    Recruiting NA

  20. Nov 2017 — Apr 2018 [monthly]

    Recruiting NA

  21. Sep 2017 — Nov 2017 [monthly]

    Recruiting NA

  22. Jun 2017 — Sep 2017 [monthly]

    Recruiting NA

  23. Mar 2017 — Jun 2017 [monthly]

    Recruiting NA

  24. Feb 2017 — Mar 2017 [monthly]

    Recruiting NA

  25. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Mar 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

RADIANCE-HTN is a randomized, double-blind, sham controlled, 2-cohort study (TRIO and SOLO) designed to demonstrate efficacy and document the safety of the Paradise Renal Denervation System in two distinct populations of hypertensive subjects.

Contact Information

Sponsor contact:
  • ReCor Medical, Inc.
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .