deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02657005

TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

A Phase 1 / 2, Dose Escalation Study of Intravenous TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

Sponsor: Oncternal Therapeutics, Inc

Conditions Sarcoma, Ewing
Interventions TK216
Updated 25 times since 2017 Last updated: Jan 29, 2025 Started: Aug 31, 2016 Primary completion: May 31, 2022 Completion: Jun 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor Decision

Other terminated trials from Oncternal Therapeutics, Inc

More terminations from Oncternal Therapeutics, Inc

A PHASE1/PHASE2 clinical study on Sarcoma, Ewing, this trial is terminated or withdrawn. The trial is conducted by Oncternal Therapeutics, Inc and has accumulated 25 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Aug 2019 · 5 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Sep 2020 · 5 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~May 2022 · 5 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

25 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Mar 2025 — Sep 2025 [monthly]

    Terminated PHASE1/PHASE2

  3. Dec 2024 — Mar 2025 [monthly]

    Terminated PHASE1/PHASE2

  4. Sep 2024 — Dec 2024 [monthly]

    Terminated PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

▶ Show 20 earlier versions

  1. Jul 2022 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

    Status: Active Not Recruiting → Terminated

  2. May 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Dec 2021 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Sep 2021 — Dec 2021 [monthly]

    Recruiting PHASE1_PHASE2

    Phase: PHASE1 → PHASE1_PHASE2

  5. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  6. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  7. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  8. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  9. Apr 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  10. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  11. Nov 2019 — Mar 2020 [monthly]

    Recruiting PHASE1

  12. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  13. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE1

  14. Mar 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  15. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  16. Aug 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  17. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  18. Nov 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  19. Feb 2017 — Nov 2017 [monthly]

    Recruiting PHASE1

  20. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Oncternal Therapeutics, Inc
Data source: Oncternal Therapeutics, Inc

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations