deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT02658734

A Study of Trastuzumab Emtansine in Indian Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Unresectable Locally Advanced or Metastatic Breast Cancer Who Have Received Prior Treatment With Trastuzumab and a Taxane

A Multicenter, Open-Label, Single-Arm, Phase IV Study of Trastuzumab Emtansine in Indian Patients With HER2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer Who Have Received Prior Treatment With Trastuzumab and a Taxane

Sponsor: Hoffmann-La Roche

Conditions HER2 Positive Breast Cancer, Metastatic Breast Cancer, Locally Advanced Breast Cancer
Interventions Trastuzumab emtansine
Updated 28 times since 2017 Last updated: Mar 31, 2021 Started: Nov 1, 2016 Primary completion: Dec 14, 2019 Completion: Dec 14, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02658734, this PHASE4 trial focuses on HER2 Positive Breast Cancer, Metastatic Breast Cancer, Locally Advanced Breast Cancer and remains completed. Sponsored by Hoffmann-La Roche, it has been updated 28 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jul 2019 · 4 months · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshot~Mar 2020 – ~Oct 2020 · 7 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Jul 2024 · 38 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Mar 2026 · 3 months · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

28 versions recorded

  1. Mar 2026 — Present [monthly]

    Completed PHASE4

  2. Dec 2025 — Mar 2026 [monthly]

    Completed PHASE4

  3. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE4

  4. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  5. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

▶ Show 23 earlier versions

  1. May 2021 — Jul 2024 [monthly]

    Completed PHASE4

  2. Mar 2021 — May 2021 [monthly]

    Completed PHASE4

  3. Jan 2021 — Mar 2021 [monthly]

    Completed PHASE4

  4. Nov 2020 — Jan 2021 [monthly]

    Completed PHASE4

  5. Oct 2020 — Nov 2020 [monthly]

    Completed PHASE4

  6. Mar 2020 — Oct 2020 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  7. Dec 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE4

  8. Nov 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE4

  9. Sep 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE4

  10. Jul 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE4

  11. Mar 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  12. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE4

  13. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE4

  14. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE4

  15. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE4

  16. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE4

  17. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE4

  18. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE4

  19. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE4

  20. Aug 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

  21. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  22. Feb 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE4

  23. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Nov 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations