deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT02661971

FLOT vs. FLOT/Ramucirumab for Perioperative Therapy of Gastric or GEJ Cancer (RAMSES) (RAMSES/FLOT7)

Perioperative RAMucirumab in Combination With FLOT Versus FLOT Alone for reSEctable eSophagogastric Adenocarcinoma - RAMSES - a Phase II/III Trial of the AIO

Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

Conditions Gastroesophageal Junction Cancer Stomach Cancer
Interventions 5-Fluorouracil Calciumfolinat Docetaxel Oxaliplatin Ramucirumab
Updated 18 times since 2017 Last updated: Jul 8, 2022 Started: Jun 30, 2016 Primary completion: Dec 31, 2021 Completion: Jun 20, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02661971, this PHASE2/PHASE3 trial focuses on Gastroesophageal Junction Cancer and Stomach Cancer and remains completed. Sponsored by Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, it has been updated 18 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Mar 2017 · 59 days · monthly snapshot~Mar 2017 – ~Jan 2018 · 10 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Jul 2019 · 5 months · monthly snapshot~Jul 2019 – ~Jan 2020 · 6 months · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

18 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  3. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

    Status: Active Not Recruiting → Completed

  4. May 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  5. Feb 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

▶ Show 13 earlier versions

  1. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Mar 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  4. May 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  5. Jan 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: Recruiting → Active Not Recruiting

  6. Jul 2019 — Jan 2020 [monthly]

    Recruiting PHASE2_PHASE3

  7. Feb 2019 — Jul 2019 [monthly]

    Recruiting PHASE2_PHASE3

  8. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE2_PHASE3

  9. Aug 2018 — Nov 2018 [monthly]

    Recruiting PHASE2_PHASE3

  10. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2_PHASE3

  11. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

  12. Mar 2017 — Jan 2018 [monthly]

    Recruiting PHASE2_PHASE3

  13. Jan 2017 — Mar 2017 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Data source: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations