deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02675790

Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa (SPRINT)

Hydroxyurea for Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa

Sponsor: Aminu Kano Teaching Hospital

Conditions Sickle Cell Anemia Sickle Cell Disease Stroke
Interventions Low Dose Hydroxyurea Moderate Dose Hydroxyurea
Updated 13 times since 2017 Last updated: Jan 16, 2022 Started: Jan 31, 2017 Primary completion: Mar 31, 2020 Completion: Mar 31, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Sickle Cell Anemia and Sickle Cell Disease and is currently completed. Aminu Kano Teaching Hospital leads this study, which shows 13 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Apr 2017 · 3 months · monthly snapshot~Apr 2017 – ~Jun 2018 · 14 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Dec 2019 · 14 months · monthly snapshot~Dec 2019 – ~Apr 2020 · 4 months · monthly snapshot~Apr 2020 – ~Sep 2020 · 5 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Jul 2024 · 29 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Feb 2022 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  4. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

▶ Show 8 earlier versions

  1. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  2. Apr 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  3. Dec 2019 — Apr 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  4. Oct 2018 — Dec 2019 [monthly]

    Recruiting PHASE3

  5. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

    Status: Active Not Recruiting → Recruiting

  6. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  7. Apr 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  8. Jan 2017 — Apr 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Aminu Kano Teaching Hospital
  • Murtala Muhammed Specialist Hospital
  • Vanderbilt University Medical Center
Data source: Vanderbilt University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations