Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya
Safety, Tolerability and Efficacy of PfSPZ Vaccine Administered by Direct Venous Inoculation (DVI) to Healthy Children and Infants 5 Months Through 9 Years of Age Living in an Area of High Malaria Transmission in Western Kenya: Age De-escalation and Dose Escalation and a Double Blind, Randomized Placebo-Controlled Trial for Safety and Efficacy
Sponsor: Centers for Disease Control and Prevention
This PHASE1/PHASE2 trial investigates Malaria and is currently completed. Centers for Disease Control and Prevention leads this study, which shows 12 recorded versions since 2016 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.
Status Flow
Change History
12 versions recorded-
Sep 2024 — Present [monthly]
Completed PHASE1/PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
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Mar 2022 — Jul 2024 [monthly]
Completed PHASE1_PHASE2
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Jan 2021 — Mar 2022 [monthly]
Completed PHASE1_PHASE2
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Sep 2019 — Jan 2021 [monthly]
Completed PHASE1_PHASE2
▶ Show 7 earlier versions
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May 2019 — Sep 2019 [monthly]
Completed PHASE1_PHASE2
Status: Active Not Recruiting → Completed
-
Nov 2018 — May 2019 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Jun 2018 — Nov 2018 [monthly]
Active Not Recruiting PHASE1_PHASE2
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May 2018 — Jun 2018 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Dec 2017 — May 2018 [monthly]
Active Not Recruiting PHASE1_PHASE2
Status: Recruiting → Active Not Recruiting
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Feb 2017 — Dec 2017 [monthly]
Recruiting PHASE1_PHASE2
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Jan 2017 — Feb 2017 [monthly]
Recruiting PHASE1_PHASE2
First recorded
Jul 2016
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Centers for Disease Control and Prevention
- Kenya Medical Research Institute
- National Institutes of Health (NIH)
- Sanaria Inc.
- University of Maryland
For direct contact, visit the study record on ClinicalTrials.gov .