deltatrials
Recruiting PHASE2 INTERVENTIONAL 15-arm NCT02693535

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer (TAPUR)

Targeted Agent and Profiling Utilization Registry (TAPUR) Study

Sponsor: American Society of Clinical Oncology

Conditions Advanced Solid Tumors Lymphoma, Non-Hodgkin Multiple Myeloma
Interventions Abemaciclib Atezolizumab and Talazoparib Dabrafenib plus Trametinib Fam-Trastuzumab Deruxtecan-Nxki (TDxD) Futibatinib Nivolumab and Ipilimumab Olaparib Palbociclib Regorafenib Sunitinib Talazoparib Temsirolimus Trastuzumab and Pertuzumab Tucatinib plus Trastuzumab Subcutaneous (SC) Vemurafenib and Cobimetinib
Updated 57 times since 2017 Last updated: Feb 11, 2026 Started: Mar 14, 2016 Primary completion: Dec 31, 2027 Completion: Dec 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Advanced Solid Tumors and Lymphoma, Non-Hodgkin and is currently actively recruiting participants. American Society of Clinical Oncology leads this study, which shows 57 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Feb 2019 · 4 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Aug 2019 · 5 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Sep 2020 · 5 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 6 months · monthly snapshot

Change History

57 versions recorded

  1. Feb 2026 — Present [monthly]

    Recruiting PHASE2

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting PHASE2

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2025 — Aug 2025 [monthly]

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  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE2

▶ Show 52 earlier versions

  1. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE2

  2. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE2

  3. Feb 2025 — Apr 2025 [monthly]

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  4. Jan 2025 — Feb 2025 [monthly]

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  5. Dec 2024 — Jan 2025 [monthly]

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  6. Oct 2024 — Dec 2024 [monthly]

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  7. Sep 2024 — Oct 2024 [monthly]

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  8. Jul 2024 — Sep 2024 [monthly]

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  9. Jun 2024 — Jul 2024 [monthly]

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  10. May 2024 — Jun 2024 [monthly]

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  11. Feb 2024 — May 2024 [monthly]

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  12. Dec 2023 — Feb 2024 [monthly]

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  13. Nov 2023 — Dec 2023 [monthly]

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  14. Oct 2023 — Nov 2023 [monthly]

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  15. Sep 2023 — Oct 2023 [monthly]

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  16. Aug 2023 — Sep 2023 [monthly]

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  17. Jun 2023 — Aug 2023 [monthly]

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  18. May 2023 — Jun 2023 [monthly]

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  19. Apr 2023 — May 2023 [monthly]

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  20. Mar 2023 — Apr 2023 [monthly]

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  21. Dec 2022 — Mar 2023 [monthly]

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  22. Sep 2022 — Dec 2022 [monthly]

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  23. Jul 2022 — Sep 2022 [monthly]

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  24. Jun 2022 — Jul 2022 [monthly]

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  25. May 2022 — Jun 2022 [monthly]

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  26. Apr 2022 — May 2022 [monthly]

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  27. Feb 2022 — Apr 2022 [monthly]

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  28. Dec 2021 — Feb 2022 [monthly]

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  29. Nov 2021 — Dec 2021 [monthly]

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  30. Sep 2021 — Nov 2021 [monthly]

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  31. Jun 2021 — Sep 2021 [monthly]

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  32. May 2021 — Jun 2021 [monthly]

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  33. Apr 2021 — May 2021 [monthly]

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  34. Mar 2021 — Apr 2021 [monthly]

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  35. Jan 2021 — Mar 2021 [monthly]

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  36. Nov 2020 — Jan 2021 [monthly]

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  37. Sep 2020 — Nov 2020 [monthly]

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  38. Apr 2020 — Sep 2020 [monthly]

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  39. Mar 2020 — Apr 2020 [monthly]

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  40. Jan 2020 — Mar 2020 [monthly]

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  41. Oct 2019 — Jan 2020 [monthly]

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  42. Aug 2019 — Oct 2019 [monthly]

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  43. Mar 2019 — Aug 2019 [monthly]

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  44. Feb 2019 — Mar 2019 [monthly]

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  45. Oct 2018 — Feb 2019 [monthly]

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  46. Aug 2018 — Oct 2018 [monthly]

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  47. Jun 2018 — Aug 2018 [monthly]

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  48. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  49. Oct 2017 — Dec 2017 [monthly]

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  50. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  51. Feb 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  52. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Mar 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • American Society of Clinical Oncology
  • AstraZeneca
  • Bayer
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • Eli Lilly and Company
  • Genentech, Inc.
  • Merck Institute for Therapeutic Research
  • Novartis
  • Pfizer
  • Seattle Genetics (now a wholly owned subsidiary of Pfizer)
  • Taiho Oncology, Inc.
Data source: American Society of Clinical Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Allentown, United States , Altamonte Springs, United States , Ann Arbor, United States , Atlanta, United States , Auburn, United States , Augusta, United States , Belfast, United States , Berkeley, United States , Bethlehem, United States and 119 more locations