deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02699606

A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma

A Phase 2a Study to Evaluate The Clinical Efficacy of JNJ-42756493, A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Patients With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Gastric Cancer, Esophageal Cancer Or Cholangiocarcinoma

Sponsor: Janssen Research & Development, LLC

Conditions Neoplasm
Interventions Erdafitinib
Updated 62 times since 2017 Last updated: Apr 24, 2025 Started: Jul 8, 2016 Primary completion: Oct 12, 2021 Completion: Mar 15, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02699606, this PHASE2 trial focuses on Neoplasm and remains completed. Sponsored by Janssen Research & Development, LLC, it has been updated 62 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~May 2017 · 4 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 9 months · monthly snapshot

Change History

62 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE2

  3. May 2025 — Sep 2025 [monthly]

    Completed PHASE2

  4. Mar 2025 — May 2025 [monthly]

    Completed PHASE2

  5. Feb 2025 — Mar 2025 [monthly]

    Completed PHASE2

▶ Show 57 earlier versions

  1. Jan 2025 — Feb 2025 [monthly]

    Completed PHASE2

  2. Sep 2024 — Jan 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2

  6. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  7. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

  8. Dec 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

  9. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE2

  10. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

  11. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  12. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  13. Apr 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  14. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  15. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE2

  16. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  17. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE2

  18. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  19. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

  20. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  21. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  22. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

  23. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE2

  24. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

  25. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  26. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  27. Dec 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE2

  28. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  29. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  30. Jun 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

  31. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  32. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

  33. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  34. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  35. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2

  36. Sep 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  37. Jul 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  38. Mar 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  39. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE2

  40. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE2

  41. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  42. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  43. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  44. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  45. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  46. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  47. Jan 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  48. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  49. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  50. Aug 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  51. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  52. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  53. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  54. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  55. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  56. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  57. Jan 2017 — May 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations