deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT02730455

Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke (ACTION2)

Multicenter, Double-Blind, Placebo-Controlled, Randomized, Parallel-Group, Dose-Ranging Study to Evaluate the Safety and Efficacy of Intravenous Natalizumab (BG00002) in Acute Ischemic Stroke

Sponsor: Biogen

Updated 13 times since 2017 Last updated: Dec 18, 2018 Started: Jul 18, 2016 Primary completion: Nov 20, 2017 Completion: Nov 20, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02730455, this PHASE2 trial focuses on Acute Ischemic Stroke and remains completed. Sponsored by Biogen, it has been updated 13 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~May 2018 · 6 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 7 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Feb 2019 — Jan 2021 [monthly]

    Completed PHASE2

Show 8 earlier versions
  1. Jun 2018 — Feb 2019 [monthly]

    Completed PHASE2

  2. May 2018 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Nov 2017 — May 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  4. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  5. Jun 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  6. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  7. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biogen
Data source: Biogen

For direct contact, visit the study record on ClinicalTrials.gov .