deltatrials
Completed OBSERVATIONAL NCT02735746

Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis (HFFLI)

Novel High Fidelity Functional Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis

Sponsor: Cedars-Sinai Medical Center

Conditions Breast Cancer Lung Cancer Mediastinum Lesion Radiation Pneumonitis
Interventions 4D Computed Tomography (CT) Cone Beam CT Low-dose Cinefluorography Pulmonary Function Tests
Updated 25 times since 2017 Last updated: Aug 21, 2025 Started: Aug 21, 2016 Primary completion: Jun 6, 2025 Completion: Jun 6, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Breast Cancer and Lung Cancer, this trial is completed. The trial is conducted by Cedars-Sinai Medical Center and has accumulated 25 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Dec 2019 · 7 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Nov 2021 · 6 months · monthly snapshot~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshot~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Nov 2023 · 8 months · monthly snapshot~Nov 2023 – ~Apr 2024 · 5 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

25 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed

    Status: Recruiting → Completed

  2. May 2025 — Sep 2025 [monthly]

    Recruiting

  3. Sep 2024 — May 2025 [monthly]

    Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  5. Apr 2024 — Jul 2024 [monthly]

    Recruiting

▶ Show 20 earlier versions

  1. Nov 2023 — Apr 2024 [monthly]

    Recruiting

  2. Mar 2023 — Nov 2023 [monthly]

    Recruiting

  3. Sep 2022 — Mar 2023 [monthly]

    Recruiting

  4. Mar 2022 — Sep 2022 [monthly]

    Recruiting

  5. Nov 2021 — Mar 2022 [monthly]

    Recruiting

  6. May 2021 — Nov 2021 [monthly]

    Recruiting

    Status: Active Not Recruiting → Recruiting

  7. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting

  8. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting

  9. Aug 2020 — Oct 2020 [monthly]

    Active Not Recruiting

  10. May 2020 — Aug 2020 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  11. Feb 2020 — May 2020 [monthly]

    Recruiting

  12. Dec 2019 — Feb 2020 [monthly]

    Recruiting

  13. May 2019 — Dec 2019 [monthly]

    Recruiting

    Phase: NA → None

  14. Feb 2019 — May 2019 [monthly]

    Recruiting NA

  15. Sep 2018 — Feb 2019 [monthly]

    Recruiting NA

  16. Jul 2018 — Sep 2018 [monthly]

    Recruiting NA

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  18. Oct 2017 — Jun 2018 [monthly]

    Recruiting NA

  19. Feb 2017 — Oct 2017 [monthly]

    Recruiting NA

  20. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cedars-Sinai Medical Center
Data source: Cedars-Sinai Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations