deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT02736695

Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia (SLD3)

Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and FTD

Sponsor: Mayo Clinic

Conditions Behavioral Variant of Frontotemporal Dementia Frontotemporal Dementia, Behavioral Variant Primary Progressive Aphasia
Interventions F-18 AV 1451
Updated 17 times since 2017 Last updated: Nov 7, 2025 Started: Jul 31, 2016 Primary completion: Aug 1, 2024 Completion: Aug 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02736695, this PHASE1 trial focuses on Behavioral Variant of Frontotemporal Dementia and Frontotemporal Dementia, Behavioral Variant and remains completed. Sponsored by Mayo Clinic, it has been updated 17 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Jun 2018 · 15 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~May 2019 · 10 months · monthly snapshot~May 2019 – ~May 2020 · 12 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~May 2022 · 12 months · monthly snapshot~May 2022 – ~Feb 2023 · 9 months · monthly snapshot~Feb 2023 – ~Apr 2024 · 14 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Jul 2025 · 3 months · monthly snapshot~Jul 2025 – ~Dec 2025 · 5 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

17 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE1

    Phase: NA → PHASE1

  2. Jul 2025 — Dec 2025 [monthly]

    Completed NA

    Status: Recruiting → Completed

  3. Apr 2025 — Jul 2025 [monthly]

    Recruiting NA

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

▶ Show 12 earlier versions

  1. Apr 2024 — Jul 2024 [monthly]

    Recruiting NA

  2. Feb 2023 — Apr 2024 [monthly]

    Recruiting NA

    Status: Enrolling By Invitation → Recruiting

  3. May 2022 — Feb 2023 [monthly]

    Enrolling By Invitation NA

  4. May 2021 — May 2022 [monthly]

    Enrolling By Invitation NA

  5. Jan 2021 — May 2021 [monthly]

    Enrolling By Invitation NA

  6. May 2020 — Jan 2021 [monthly]

    Enrolling By Invitation NA

  7. May 2019 — May 2020 [monthly]

    Enrolling By Invitation NA

    Status: Completed → Enrolling By Invitation

  8. Jul 2018 — May 2019 [monthly]

    Completed NA

    Status: Recruiting → Completed

  9. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  10. Mar 2017 — Jun 2018 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  11. Feb 2017 — Mar 2017 [monthly]

    Not Yet Recruiting NA

  12. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting NA

    First recorded

Jul 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mayo Clinic
  • National Institute of Neurological Disorders and Stroke (NINDS)
Data source: Mayo Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations