deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02743377

PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome

PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of Mccune-Albright Syndrome

Sponsor: National Institute of Mental Health (NIMH)

Conditions Nervous System Disease
Interventions Brain PET Imaging with 11C Rolipram Whole Body PET Baseline with 11C Rolipram Whole Body PET Blocked with Roflumilast
Updated 16 times since 2017 Last updated: Sep 24, 2020 Started: Apr 4, 2018 Primary completion: Oct 23, 2019 Completion: May 19, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Nervous System Disease and is currently completed. National Institute of Mental Health (NIMH) leads this study, which shows 16 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~May 2018 · 10 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Apr 2020 · 20 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

16 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

  5. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE1_PHASE2

▶ Show 11 earlier versions

  1. Nov 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  2. Jun 2020 — Nov 2020 [monthly]

    Completed PHASE1_PHASE2

    Status: Recruiting → Completed

  3. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1_PHASE2

  4. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  5. Aug 2018 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1_PHASE2

  8. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  9. Jul 2017 — May 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    Status: Recruiting → Not Yet Recruiting

  10. Feb 2017 — Jul 2017 [monthly]

    Recruiting PHASE1_PHASE2

  11. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Mental Health (NIMH)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations