deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02757326

ABC294640 (Opaganib) in Refractory / Relapsed Multiple Myeloma (ABC-103)

A Phase Ib/II Safety and Efficacy Study of ABC294640 in Patients With Refractory or Relapsed Multiple Myeloma Who Have Previously Been Treated With Proteasome Inhibitors and Immunomodulatory Drugs

Sponsor: Apogee Biotechnology Corporation

Interventions Opaganib
Updated 11 times since 2017 Last updated: May 24, 2021 Started: Dec 13, 2016 Primary completion: May 31, 2019 Completion: May 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Expiration of National Cancer Institute (NCI) funding of the study.

Listed as NCT02757326, this PHASE1/PHASE2 trial focuses on Multiple Myeloma and remains terminated or withdrawn. Sponsored by Apogee Biotechnology Corporation, it has been updated 11 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshotNot Yet Recruiting~Mar 2017 – ~Jun 2018 · 15 months · monthly snapshotRecruiting~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshotRecruiting~Jun 2019 – ~Jan 2021 · 19 months · monthly snapshotTerminated~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotTerminated~Sep 2021 – ~Dec 2022 · 15 months · monthly snapshotTerminated~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotTerminated~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 21 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE1_PHASE2

  5. Sep 2021 — Dec 2022 [monthly]

    Terminated PHASE1_PHASE2

Show 6 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Terminated PHASE1_PHASE2

  2. Jun 2019 — Jan 2021 [monthly]

    Terminated PHASE1_PHASE2

    Status: RecruitingTerminated

  3. Jun 2018 — Jun 2019 [monthly]

    Recruiting PHASE1_PHASE2

  4. Mar 2017 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Feb 2017 — Mar 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Dec 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Apogee Biotechnology Corporation
  • Duke University
  • National Cancer Institute (NCI)
  • RedHill Biopharma Limited
Data source: RedHill Biopharma Limited

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations