deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02767661

Metronomic Capecitabine Plus Aromatase Inhibitor for First Line Treatment in HR(+), Her2(-) Metastatic Breast Cancer (MECCA)

A Phase 3 Randomized Controlled Study of Metronomic Capecitabine Combined With Aromatase Inhibitor Versus Aromatase Inhibitor Alone for First Line Treatment in Hormone Receptor-positive, Her2-negative Metastatic Breast Cancer

Sponsor: Sun Yat-Sen University Cancer Center

Conditions Breast Cancer
Updated 11 times since 2017 Last updated: Feb 24, 2026 Started: Jul 19, 2017 Primary completion: Aug 25, 2023 Completion: Aug 25, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02767661, this PHASE3 trial focuses on Breast Cancer and remains completed. Sponsored by Sun Yat-Sen University Cancer Center, it has been updated 11 times since 2017, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Jun 2017 · 5 months · monthly snapshotNot Yet Recruiting~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshotNot Yet Recruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2023 · 25 months · monthly snapshotRecruiting~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshotActive Not Recruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotActive Not Recruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshotCompleted~Mar 2026 – present · 4 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Mar 2026 — Present [monthly]

    Completed PHASE3

  2. Feb 2026 — Mar 2026 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

Show 6 earlier versions
  1. Feb 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Jan 2021 — Feb 2023 [monthly]

    Recruiting PHASE3

  3. Jun 2018 — Jan 2021 [monthly]

    Recruiting PHASE3

  4. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  5. Jun 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE3

  6. Jan 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sun Yat-Sen University Cancer Center
  • Sun Yat-sen University
Data source: Sun Yat-sen University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations