deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT02770170

Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis

A Double-blind, Randomised, Placebo-controlled Trial Evaluating the Effect of BI 655064 Administered as Sub-cutaneous Injections, on Renal Response After One Year of Treatment, in Patients With Active Lupus Nephritis

Sponsor: Boehringer Ingelheim

Conditions Lupus Nephritis
Interventions BI 655064 dose 1 BI 655064 dose 2 BI 655064 dose 3 Placebo
Updated 43 times since 2017 Last updated: Oct 8, 2025 Started: May 16, 2016 Primary completion: Jun 23, 2020 Completion: Aug 18, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Lupus Nephritis and is currently completed. Boehringer Ingelheim leads this study, which shows 43 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Apr 2017 · 31 days · monthly snapshot~Apr 2017 – ~May 2017 · 30 days · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Nov 2017 · 2 months · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 10 months · monthly snapshot

Change History

43 versions recorded

  1. Nov 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Nov 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE2

▶ Show 38 earlier versions

  1. Jan 2021 — Sep 2021 [monthly]

    Completed PHASE2

  2. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

  6. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  7. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2

  8. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  9. Nov 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Aug 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  11. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  12. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  13. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  14. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  15. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  16. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  17. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  18. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  19. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  20. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  21. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  22. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  23. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  24. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  25. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  26. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE2

  27. Jan 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  28. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  29. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  30. Sep 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  31. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  32. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  33. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

  34. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  35. Apr 2017 — May 2017 [monthly]

    Recruiting PHASE2

  36. Mar 2017 — Apr 2017 [monthly]

    Recruiting PHASE2

  37. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE2

  38. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boehringer Ingelheim
Data source: Boehringer Ingelheim

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aguascalientes, Mexico , Angeles City, Philippines , Athens, Greece , Atlanta, United States , Bangkok, Thailand , Barcelona, Spain , Belgrade, Serbia , Bialystok, Poland , Cambridge, United Kingdom , Cebu City, Philippines and 54 more locations