deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT02788461

Assessing the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy (PET-BOOST)

A Randomized Phase II Trial to Assess the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Conditions Non-Small Cell Lung Cancer
Interventions Chemoradiotherapy Chemoradiotherapy with Integrated Boost Dose
Updated 18 times since 2017 Last updated: Sep 12, 2025 Started: May 31, 2016 Primary completion: Apr 30, 2026 Completion: Apr 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Non-Small Cell Lung Cancer and is currently ongoing. London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's leads this study, which shows 18 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Dec 2017 · 11 months · monthly snapshot~Dec 2017 – ~Apr 2018 · 4 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Mar 2019 · 7 months · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jan 2021 · 21 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2022 · 14 months · monthly snapshot~May 2022 – ~Mar 2024 · 22 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

18 versions recorded

  1. Oct 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting NA

  3. Apr 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

  4. Jan 2025 — Apr 2025 [monthly]

    Active Not Recruiting NA

  5. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting NA

▶ Show 13 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

  2. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  3. May 2022 — Mar 2024 [monthly]

    Recruiting NA

  4. Mar 2021 — May 2022 [monthly]

    Recruiting NA

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting NA

  6. Apr 2019 — Jan 2021 [monthly]

    Recruiting NA

  7. Mar 2019 — Apr 2019 [monthly]

    Recruiting NA

  8. Aug 2018 — Mar 2019 [monthly]

    Recruiting NA

  9. Jul 2018 — Aug 2018 [monthly]

    Recruiting NA

  10. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  11. Apr 2018 — Jun 2018 [monthly]

    Recruiting NA

  12. Dec 2017 — Apr 2018 [monthly]

    Recruiting NA

  13. Jan 2017 — Dec 2017 [monthly]

    Recruiting NA

    First recorded

May 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Data source: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations