deltatrials
Recruiting NA INTERVENTIONAL 1-arm NCT02795052

Neurologic Stem Cell Treatment Study (NEST)

Neurologic Bone Marrow Derived Stem Cell Treatment Study

Sponsor: MD Stem Cells

Conditions ALS Alzheimer Disease Amyotrophic Lateral Sclerosis Cadasil Cerebral Hemorrhage Cerebral Infarction Cerebral Ischemia Cerebral Stroke Chronic Traumatic Encephalopathy Cognitive Impairment Dementia Diabetic Neuropathies Frontotemporal Dementia Lewy Body Disease Lewy Body Variant of Alzheimer Disease MSA - Multiple System Atrophy Multi-System Degeneration Nervous System Diseases Neurodegenerative Diseases Neurologic Disorders Neurological Disorders Neuropathy Parkinson Progressive Supranuclear Palsy Stroke Traumatic Brain Injury
Interventions Intravenous and Intranasal BMSC
Updated 25 times since 2017 Last updated: Jun 3, 2025 Started: Jun 30, 2016 Primary completion: Jul 31, 2026 Completion: Jul 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates ALS and Alzheimer Disease and is currently actively recruiting participants. MD Stem Cells leads this study, which shows 25 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~May 2017 · 4 months · monthly snapshot~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Jul 2019 · 6 months · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Apr 2020 · 5 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshot~Oct 2021 – ~May 2022 · 7 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jul 2023 · 7 months · monthly snapshot~Jul 2023 – ~May 2024 · 10 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – present · 12 months · monthly snapshot

Change History

25 versions recorded

  1. Jul 2025 — Present [monthly]

    Recruiting NA

  2. Jun 2025 — Jul 2025 [monthly]

    Recruiting NA

  3. Apr 2025 — Jun 2025 [monthly]

    Recruiting NA

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

▶ Show 20 earlier versions

  1. May 2024 — Jul 2024 [monthly]

    Recruiting NA

  2. Jul 2023 — May 2024 [monthly]

    Recruiting NA

  3. Dec 2022 — Jul 2023 [monthly]

    Recruiting NA

  4. Sep 2022 — Dec 2022 [monthly]

    Recruiting NA

  5. May 2022 — Sep 2022 [monthly]

    Recruiting NA

  6. Oct 2021 — May 2022 [monthly]

    Recruiting NA

  7. Mar 2021 — Oct 2021 [monthly]

    Recruiting NA

  8. Jan 2021 — Mar 2021 [monthly]

    Recruiting NA

  9. Oct 2020 — Jan 2021 [monthly]

    Recruiting NA

  10. Aug 2020 — Oct 2020 [monthly]

    Recruiting NA

  11. Jul 2020 — Aug 2020 [monthly]

    Recruiting NA

  12. Apr 2020 — Jul 2020 [monthly]

    Recruiting NA

  13. Nov 2019 — Apr 2020 [monthly]

    Recruiting NA

  14. Sep 2019 — Nov 2019 [monthly]

    Recruiting NA

  15. Jul 2019 — Sep 2019 [monthly]

    Recruiting NA

  16. Jan 2019 — Jul 2019 [monthly]

    Recruiting NA

  17. Dec 2018 — Jan 2019 [monthly]

    Recruiting NA

  18. Jun 2018 — Dec 2018 [monthly]

    Recruiting NA

  19. May 2017 — Jun 2018 [monthly]

    Recruiting NA

  20. Jan 2017 — May 2017 [monthly]

    Recruiting NA

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MD Stem Cells
Data source: MD Stem Cells

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations