deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02836574

A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease

A Phase 2 Prospective, Randomized, Double-Arm, Deferred Treatment, Open Label, Repeat Dose, Safety and Efficacy Study of Renal Autologous Cell Therapy (REACT) in Subjects With Type 2 Diabetes and Chronic Kidney Disease

Sponsor: CTI Clinical Trial and Consulting Services

Conditions Chronic Kidney Disease Type 2 Diabetes Mellitus
Interventions Renal Autologous Cell Therapy (REACT) Renal Biopsy
Updated 21 times since 2017 Last updated: Aug 21, 2025 Started: Sep 30, 2016 Primary completion: Dec 31, 2023 Completion: Dec 31, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02836574, this PHASE2 trial focuses on Chronic Kidney Disease and Type 2 Diabetes Mellitus and remains completed. Sponsored by CTI Clinical Trial and Consulting Services, it has been updated 21 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~May 2019 · 10 months · monthly snapshot~May 2019 – ~Jul 2020 · 14 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Nov 2022 · 8 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

21 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Nov 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Nov 2024 [monthly]

    Completed PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 16 earlier versions

  1. Feb 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Nov 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Mar 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  5. Oct 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  6. Jun 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

  7. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  10. Jul 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  11. May 2019 — Jul 2020 [monthly]

    Recruiting PHASE2

  12. Jul 2018 — May 2019 [monthly]

    Recruiting PHASE2

  13. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  14. Aug 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  15. Feb 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  16. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Sep 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CTI Clinical Trial and Consulting Services
  • Prokidney
Data source: Prokidney

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Allentown, United States , Ann Arbor, United States , Baton Rouge, United States , Chapel Hill, United States , Chicago, United States , Denver, United States , Gainesville, United States , Kalamazoo, United States , Louisville, United States , Madison, United States and 6 more locations