deltatrials
Unknown PHASE3 INTERVENTIONAL 4-arm NCT02842931

R-Dose-adjusted (DA) - EPOCH-21 Versus R-modified Non-Hodgkin Lymphoma (NHL)-Berlin-Frankfurt-Munster (BFM)-90 Program (mNHL-BFM-90) and Autologous Stem Cells Transplantation (Auto-SCT) in DLBCL With Poor Prognosis

Multicenter, Randomized, Controlled (Comparative), Open, Prospective Study Evaluating an Efficacy of R-DA-EPOCH-21, R-mNHL-BFM-90 and (Auto-SCT)in Patients With DLBCL

Sponsor: National Research Center for Hematology

Conditions Diffuse Large B-Cell Lymphoma
Interventions R-DA-EPOCH-21 R-DA-EPOCH-21 + auto-SCT R-mNHL-BFM-90 R-mNHL-BFM-90 + auto-SCT
Updated 7 times since 2017 Last updated: Jul 20, 2016 Started: Feb 28, 2015 Primary completion: Feb 29, 2020 Completion: Feb 28, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02842931, this PHASE3 trial focuses on Diffuse Large B-Cell Lymphoma and remains ongoing. Sponsored by National Research Center for Hematology, it has been updated 7 times since 2015, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotRecruiting~Jan 2021 – ~Mar 2023 · 26 months · monthly snapshotRecruiting~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE3

    Status: Unknown Status → Unknown

  4. Mar 2023 — Jul 2024 [monthly]

    Unknown Status PHASE3

    Status: Recruiting → Unknown Status

  5. Jan 2021 — Mar 2023 [monthly]

    Recruiting PHASE3

▶ Show 2 earlier versions

  1. Jun 2018 — Jan 2021 [monthly]

    Recruiting PHASE3

  2. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Research Center for Hematology
  • National Research Center for Hematology, Russia
Data source: National Research Center for Hematology, Russia

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations