deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02852486

Study of Imatinib Discontinuation in Chronic Myeloid Leukemia With Deep Molecular Response (EDI-PIO)

Pilot Study of Imatinib Discontinuation in Patients With Chronic Myeloid Leukemia With Deep Molecular Response - Evaluation of Pioglitazone in Treatment-free Remission (EDI-PIO)

Sponsor: University of Campinas, Brazil

Updated 12 times since 2017 Last updated: Mar 25, 2025 Started: Jun 22, 2016 Primary completion: Feb 7, 2024 Completion: Feb 7, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02852486, this PHASE2 trial focuses on Leukemia, Chronic Myeloid and remains completed. Sponsored by University of Campinas, Brazil, it has been updated 12 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Oct 2017 · 9 months · monthly snapshotRecruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotRecruiting~Jun 2018 – ~May 2019 · 11 months · monthly snapshotRecruiting~May 2019 – ~Dec 2020 · 19 months · monthly snapshotActive Not Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotActive Not Recruiting~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotActive Not Recruiting~Dec 2022 – ~Jan 2024 · 13 months · monthly snapshotActive Not Recruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotActive Not Recruiting~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshotCompleted~Jun 2025 – present · 15 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Jun 2025 — Present [monthly]

    Completed PHASE2

  2. Apr 2025 — Jun 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 7 earlier versions
  1. Dec 2022 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Jan 2021 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  3. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  4. May 2019 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2

  6. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  7. Jan 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Campinas, Brazil
Data source: University of Campinas, Brazil

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations