A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL) (CheckMate 647)
A Phase 2, Open-label, Single-arm, Two-cohort Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Relapsed/Refractory Primary Testicular Lymphoma (PTL)
Sponsor: Bristol-Myers Squibb
A PHASE2 clinical study on Lymphoma, this trial is completed. The trial is conducted by Bristol-Myers Squibb and has accumulated 23 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
23 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE2
-
Jan 2022 — Jul 2024 [monthly]
Completed PHASE2
-
Dec 2021 — Jan 2022 [monthly]
Completed PHASE2
Status: Active Not Recruiting → Completed
▶ Show 18 earlier versions
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Jan 2021 — Dec 2021 [monthly]
Active Not Recruiting PHASE2
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Nov 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE2
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Nov 2019 — Nov 2020 [monthly]
Active Not Recruiting PHASE2
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Aug 2019 — Nov 2019 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Feb 2019 — Aug 2019 [monthly]
Recruiting PHASE2
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Nov 2018 — Feb 2019 [monthly]
Recruiting PHASE2
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Oct 2018 — Nov 2018 [monthly]
Recruiting PHASE2
-
Sep 2018 — Oct 2018 [monthly]
Recruiting PHASE2
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Aug 2018 — Sep 2018 [monthly]
Recruiting PHASE2
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Jun 2018 — Aug 2018 [monthly]
Recruiting PHASE2
-
Aug 2017 — Jun 2018 [monthly]
Recruiting PHASE2
-
Jul 2017 — Aug 2017 [monthly]
Recruiting PHASE2
Status: Active Not Recruiting → Recruiting
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Jun 2017 — Jul 2017 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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May 2017 — Jun 2017 [monthly]
Recruiting PHASE2
Status: Active Not Recruiting → Recruiting
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Apr 2017 — May 2017 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Mar 2017 — Apr 2017 [monthly]
Recruiting PHASE2
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Feb 2017 — Mar 2017 [monthly]
Recruiting PHASE2
-
Jan 2017 — Feb 2017 [monthly]
Recruiting PHASE2
First recorded
Oct 2016
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Bristol-Myers Squibb
- Ono Pharmaceutical Co. Ltd
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Barretos, Brazil , Birmingham, United States , Bordeaux, France , Boston, United States , Budapest, Hungary , Caen, France , Chuo-ku, Japan , Dallas, United States , Debrecen, Hungary , Detroit, United States and 38 more locations