Terminated NA INTERVENTIONAL 3-arm NCT02863380

Personalized rTMS for Resistant Depression

Validation of Personalized Antidepressant Treatment by Neuromodulation - Pilot Study

Sponsor: University Hospital, Strasbourg, France

Conditions Depressive Disorder Treatment-Resistant

Interventions Classical rTMS (transcranial magnetic stimulation) Classical tDCS (transcranial direct current stimulation) Functional magnetic resonance imaging used to individualize rTMS protocol Individualized rTMS (transcranial magnetic stimulation)

Updated 12 times since 2017 Last updated: Sep 22, 2025 Started: May 4, 2016 Primary completion: Jan 21, 2021 Completion: Jan 21, 2021

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The research objectives are achieved, demonstrating the feasibility and superiority of the personalized approach. It was no longer justified to continue the inclusions in this 'proof of concept' type study.

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This NA trial investigates Depressive Disorder and Treatment-Resistant and is currently terminated or withdrawn. University Hospital, Strasbourg, France leads this study, which shows 12 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

12 versions recorded

Oct 2025 — Present [monthly]

Terminated NA
Sep 2024 — Oct 2025 [monthly]

Terminated NA
Jul 2024 — Sep 2024 [monthly]

Terminated NA
Apr 2023 — Jul 2024 [monthly]

Terminated NA
May 2022 — Apr 2023 [monthly]

Terminated NA

Status: Recruiting → Terminated

▶ Show 7 earlier versions

Jan 2021 — May 2022 [monthly]

Recruiting NA
Sep 2020 — Jan 2021 [monthly]

Recruiting NA
May 2019 — Sep 2020 [monthly]

Recruiting NA
Jun 2018 — May 2019 [monthly]

Recruiting NA
Apr 2018 — Jun 2018 [monthly]

Recruiting NA
Oct 2017 — Apr 2018 [monthly]

Recruiting NA

Phase: PHASE1_PHASE2 → NA
Jan 2017 — Oct 2017 [monthly]

Recruiting PHASE1_PHASE2

First recorded

May 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

University Hospital, Strasbourg, France

Data source: University Hospital, Strasbourg, France

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Strasbourg, France