deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT02869789

An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers

A Phase 3b/4 Safety Trial of Flat Dose Nivolumab In Combination With Ipilimumab in Participants With Non-Small Cell Lung Cancer

Sponsor: Bristol-Myers Squibb

Conditions Lung Cancer
Interventions Nivolumab in combination with Ipilimumab
Updated 33 times since 2017 Last updated: Jun 12, 2023 Started: Oct 5, 2016 Primary completion: May 13, 2022 Completion: May 13, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Lung Cancer, this trial is completed. The trial is conducted by Bristol-Myers Squibb and has accumulated 33 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Apr 2017 · 31 days · monthly snapshot~Apr 2017 – ~May 2017 · 30 days · monthly snapshot~May 2017 – ~Jul 2017 · 2 months · monthly snapshot~Jul 2017 – ~Oct 2017 · 3 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~May 2019 · 4 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~May 2020 · 9 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jul 2023 · 10 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

33 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE4

  5. Sep 2022 — Jul 2023 [monthly]

    Completed PHASE4

▶ Show 28 earlier versions

  1. Jun 2022 — Sep 2022 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  2. Mar 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE4

  3. Jan 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE4

  4. Sep 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE4

  5. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE4

  6. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE4

  7. Jul 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE4

  8. May 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  9. Aug 2019 — May 2020 [monthly]

    Recruiting PHASE4

  10. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE4

  11. May 2019 — Jul 2019 [monthly]

    Recruiting PHASE4

  12. Jan 2019 — May 2019 [monthly]

    Recruiting PHASE4

  13. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE4

  14. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE4

  15. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE4

  16. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE4

  17. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE4

  18. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE4

  19. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE4

  20. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE4

  21. Dec 2017 — Feb 2018 [monthly]

    Recruiting PHASE4

    Phase: PHASE3 → PHASE4

  22. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  23. Jul 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  24. May 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  25. Apr 2017 — May 2017 [monthly]

    Recruiting PHASE3

  26. Mar 2017 — Apr 2017 [monthly]

    Recruiting PHASE3

  27. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  28. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
Data source: Bristol-Myers Squibb

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Allentown, United States , Antalya, Turkey (Türkiye) , Athens, Greece , Athens, United States , Atlanta, United States , Austin, United States , Bakersfield, United States , Barcelona, Spain , Barretos, Brazil and 118 more locations