Efficacy Study of Hydroxychloroquine to Treat High-risk Coronary Artery Disease. (CHANGAN)
Hydroxychloroquine Assessment of Management Study in Coronary Artery Disease After Angiography.
Sponsor: First Affiliated Hospital Xi'an Jiaotong University
Listed as NCT02874287, this PHASE4 trial focuses on Coronary Artery Disease and remains completed. Sponsored by First Affiliated Hospital Xi'an Jiaotong University, it has been updated 10 times since 2017, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.
Study Description(click to expand)This double blind, placebo, randomized controlled trial is going to assess if hydroxychloroquine could improve the high sensitivity C-reaction protein, blood lipid, blood glucose and blood pressure, also whether hydroxychloroquine could affect the secretion of inflammatory cytokines and the M1/M2 phenotype polarization of macrophages in patients with high-risk coronary artery disease.
This double blind, placebo, randomized controlled trial is going to assess if hydroxychloroquine could improve the high sensitivity C-reaction protein, blood lipid, blood glucose and blood pressure, also whether hydroxychloroquine could affect the secretion of inflammatory cytokines and the M1/M2 phenotype polarization of macrophages in patients with high-risk coronary artery disease.
Status Flow
Change History
10 versions recorded-
Jan 2026 — Present [monthly]
Completed PHASE4
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Sep 2025 — Present [monthly]
Completed PHASE4
-
Sep 2024 — Sep 2025 [monthly]
Completed PHASE4
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE4
-
Sep 2021 — Jul 2024 [monthly]
Completed PHASE4
Status: Unknown Status → Completed
▶ Show 5 earlier versions
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Jan 2021 — Sep 2021 [monthly]
Unknown Status PHASE4
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Dec 2019 — Jan 2021 [monthly]
Unknown Status PHASE4
Status: Recruiting → Unknown Status
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Jun 2018 — Dec 2019 [monthly]
Recruiting PHASE4
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Dec 2017 — Jun 2018 [monthly]
Recruiting PHASE4
Status: Not Yet Recruiting → Recruiting
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Jan 2017 — Dec 2017 [monthly]
Not Yet Recruiting PHASE4
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- First Affiliated Hospital Xi'an Jiaotong University
For direct contact, visit the study record on ClinicalTrials.gov .