Completed PHASE4 INTERVENTIONAL 4-arm NCT02876601

Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of Defibrotide (LPS_DF)

Defibrotide in the Human Endotoxemia Model -- an Exploratory Trial Investigating the Effects and the Mechanisms of Defibrotide

Sponsor: Bernd Jilma

Conditions Endotoxemia Healthy Volunteers

Interventions Defibrotide Lipopolysaccharide Placebo (0.9% sodium chloride bolus) Placebo (0.9% sodium chloride)

Updated 10 times since 2017 Last updated: Dec 2, 2019 Started: Apr 18, 2017 Primary completion: Feb 12, 2018 Completion: Feb 12, 2018

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Endotoxemia and Healthy Volunteers and is currently completed. Bernd Jilma leads this study, which shows 10 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

10 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4
Sep 2020 — Jan 2021 [monthly]

Completed PHASE4
Jan 2020 — Sep 2020 [monthly]

Completed PHASE4

▶ Show 5 earlier versions

Feb 2019 — Jan 2020 [monthly]

Completed PHASE4

Status: Recruiting → Completed
Jun 2018 — Feb 2019 [monthly]

Recruiting PHASE4
Sep 2017 — Jun 2018 [monthly]

Recruiting PHASE4

Status: Not Yet Recruiting → Recruiting
May 2017 — Sep 2017 [monthly]

Not Yet Recruiting PHASE4
Jan 2017 — May 2017 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Bernd Jilma

Data source: Medical University of Vienna

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Vienna, Austria