deltatrials
Recruiting NA INTERVENTIONAL 2-arm NCT02898181

Low Level Tragus Stimulation in Acute Decompensated Heart Failure (TREAT-HF)

Low Level Transcutaneous Tragus Stimulation to Reduce Inflammation, Dyspnea and Improve Heart Rate Variability in Acute Decompensated Heart Failure

Sponsor: University of Oklahoma

Conditions Acute Decompensated Heart Failure
Interventions Neuromodulation
Updated 15 times since 2017 Last updated: May 21, 2025 Started: Sep 30, 2016 Primary completion: Sep 30, 2026 Completion: Sep 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Acute Decompensated Heart Failure, this trial is actively recruiting participants. The trial is conducted by University of Oklahoma and has accumulated 15 data snapshots since 2016. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2020 · 18 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Sep 2023 · 20 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jun 2025 · 8 months · monthly snapshot~Jun 2025 – present · 13 months · monthly snapshot

Change History

15 versions recorded

  1. Jun 2025 — Present [monthly]

    Recruiting NA

  2. Oct 2024 — Jun 2025 [monthly]

    Recruiting NA

  3. Sep 2024 — Oct 2024 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Sep 2023 — Jul 2024 [monthly]

    Recruiting NA

▶ Show 10 earlier versions

  1. Jan 2022 — Sep 2023 [monthly]

    Recruiting NA

    Status: Active Not Recruiting → Recruiting

  2. Jan 2021 — Jan 2022 [monthly]

    Active Not Recruiting NA

  3. May 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  4. Feb 2020 — May 2020 [monthly]

    Recruiting NA

  5. Aug 2018 — Feb 2020 [monthly]

    Recruiting NA

  6. Jun 2018 — Aug 2018 [monthly]

    Recruiting NA

  7. Feb 2018 — Jun 2018 [monthly]

    Recruiting NA

  8. Oct 2017 — Feb 2018 [monthly]

    Recruiting NA

  9. Feb 2017 — Oct 2017 [monthly]

    Recruiting NA

  10. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Sep 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Oklahoma
Data source: University of Oklahoma

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations