deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02899611

A Dose Ranging Pilot Study for Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal Seizures

A Dose Ranging Pilot Study to Assess Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Sponsor: Cerebral Therapeutics LLC

Conditions Epilepsy
Interventions Valproate
Updated 11 times since 2017 Last updated: Mar 14, 2023 Started: Aug 31, 2016 Primary completion: Jun 1, 2021 Completion: Jun 1, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Epilepsy and is currently completed. Cerebral Therapeutics LLC leads this study, which shows 11 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2018 · 13 months · monthly snapshotRecruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotRecruiting~Jun 2018 – ~Sep 2019 · 15 months · monthly snapshotRecruiting~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshotRecruiting~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotActive Not Recruiting~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Apr 2023 · 19 months · monthly snapshotCompleted~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Sep 2021 — Apr 2023 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not Recruiting → Completed

  5. Feb 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

▶ Show 6 earlier versions

  1. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Dec 2019 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Sep 2019 — Dec 2019 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jun 2018 — Sep 2019 [monthly]

    Recruiting PHASE1_PHASE2

  5. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jan 2017 — Feb 2018 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cerebral Therapeutics LLC
  • Neuroscience Trials Australia
Data source: Cerebral Therapeutics LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations