deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02899728

Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer

A Phase II Study of Olaparib Plus Cediranib in Combination With Standard Therapy for Small Cell Lung Cancer

Sponsor: National Cancer Institute (NCI)

Conditions Extensive Stage Lung Small Cell Carcinoma
Interventions Carboplatin Cediranib Cediranib Maleate Cisplatin Etoposide Olaparib
Updated 32 times since 2017 Last updated: Sep 22, 2023 Started: Mar 30, 2018 Primary completion: Mar 17, 2020 Completion: Mar 17, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Inadequate accrual rate

Other terminated trials from National Cancer Institute (NCI)

See all terminations from National Cancer Institute (NCI)

Other Extensive Stage Lung Small Cell Carcinoma trials with similar outcome

Browse all Extensive Stage Lung Small Cell Carcinoma trials

This PHASE2 trial investigates Extensive Stage Lung Small Cell Carcinoma and is currently terminated or withdrawn. National Cancer Institute (NCI) leads this study, which shows 32 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Feb 2018 · 8 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Nov 2023 · 30 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

32 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Nov 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  5. May 2021 — Nov 2023 [monthly]

    Terminated PHASE2

▶ Show 27 earlier versions

  1. Jan 2021 — May 2021 [monthly]

    Terminated PHASE2

  2. Jun 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  3. Apr 2020 — Jun 2020 [monthly]

    Terminated PHASE2

    Status: Suspended → Terminated

  4. Mar 2020 — Apr 2020 [monthly]

    Suspended PHASE2

  5. Feb 2020 — Mar 2020 [monthly]

    Suspended PHASE2

  6. Jan 2020 — Feb 2020 [monthly]

    Suspended PHASE2

  7. Dec 2019 — Jan 2020 [monthly]

    Suspended PHASE2

  8. Nov 2019 — Dec 2019 [monthly]

    Suspended PHASE2

  9. Oct 2019 — Nov 2019 [monthly]

    Suspended PHASE2

  10. Sep 2019 — Oct 2019 [monthly]

    Suspended PHASE2

  11. Aug 2019 — Sep 2019 [monthly]

    Suspended PHASE2

  12. Jul 2019 — Aug 2019 [monthly]

    Suspended PHASE2

  13. Jun 2019 — Jul 2019 [monthly]

    Suspended PHASE2

  14. May 2019 — Jun 2019 [monthly]

    Suspended PHASE2

  15. Mar 2019 — May 2019 [monthly]

    Suspended PHASE2

  16. Jan 2019 — Mar 2019 [monthly]

    Suspended PHASE2

  17. Nov 2018 — Jan 2019 [monthly]

    Suspended PHASE2

  18. Aug 2018 — Nov 2018 [monthly]

    Suspended PHASE2

  19. Jul 2018 — Aug 2018 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  20. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

    Status: Suspended → Recruiting

  21. May 2018 — Jun 2018 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  22. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE2

  23. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

    Status: Suspended → Recruiting

  24. Jun 2017 — Feb 2018 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  25. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  26. Feb 2017 — May 2017 [monthly]

    Not Yet Recruiting PHASE2

  27. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Boston, United States , Charlottesville, United States , City of Saint Peters, United States , Cleveland, United States , Columbus, United States , Creve Coeur, United States , Jacksonville, United States , Lexington, United States , Los Angeles, United States and 8 more locations