deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02937285

National Multicenter, Controlled, Single-blind Study With Two Parallel Groups Evaluating the Safety and Efficacy of Sequential Treatment With Mitoxantrone and Interferon Versus Interferon Alone in Patients With Strong Risk of Progression in the Initial Phase of Multiple Sclerosis (MITOX-REBIF)

National Multicenter, Controlled, Single-blind Study With Two Parallel Groups Evaluating the Safety and Efficacy of Sequential Treatment With Mitoxantrone and Interferon Beta-1a (REBIF 44mg 3 Times / Week) Versus Interferon Alone in Patients With Strong Risk of Progression in the Initial Phase of Multiple Sclerosis

Sponsor: Rennes University Hospital

Updated 8 times since 2017 Last updated: Mar 28, 2023 Started: Dec 6, 2010 Primary completion: May 28, 2020 Completion: May 28, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Multiple Sclerosis and is currently completed. Rennes University Hospital leads this study, which shows 8 recorded versions since 2010 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Nov 2017 · 10 months · monthly snapshotRecruiting~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Dec 2020 · 30 months · monthly snapshotActive Not Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotUnknown Status~Jan 2021 – ~Apr 2023 · 27 months · monthly snapshotUnknown Status~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Unknown StatusCompleted

  4. Jan 2021 — Apr 2023 [monthly]

    Unknown Status PHASE3

  5. Dec 2020 — Jan 2021 [monthly]

    Unknown Status PHASE3

    Status: Active Not RecruitingUnknown Status

Show 3 earlier versions
  1. Jun 2018 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  2. Nov 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  3. Jan 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

    First recorded

Dec 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Rennes University Hospital
Data source: Rennes University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations