deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT02942173

CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT

A Phase II Prospective Randomized Trial of Donor T-memory Cells (CD45RA Depleted) Infusion for Prevention of Infections After Allogeneic TcRαβ/CD19-depleted Hematopoietic Stem Cell Transplantation

Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Updated 12 times since 2017 Last updated: Mar 15, 2023 Started: Oct 31, 2016 Primary completion: Aug 21, 2019 Completion: Aug 21, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2/PHASE3 clinical study on Graft-versus-Host Disease and GvHD, this trial is completed. The trial is conducted by Federal Research Institute of Pediatric Hematology, Oncology and Immunology and has accumulated 12 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Dec 2017 · 11 months · monthly snapshotRecruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotRecruiting~Oct 2018 – ~Jan 2019 · 3 months · monthly snapshotRecruiting~Jan 2019 – ~Mar 2020 · 14 months · monthly snapshotRecruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotActive Not Recruiting~Mar 2022 – ~Apr 2023 · 13 months · monthly snapshotUnknown Status~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2/PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  4. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

    Status: Unknown StatusCompleted

  5. Mar 2022 — Apr 2023 [monthly]

    Unknown Status PHASE2_PHASE3

    Status: Active Not RecruitingUnknown Status

Show 7 earlier versions
  1. Jan 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  3. Jan 2019 — Mar 2020 [monthly]

    Recruiting PHASE2_PHASE3

  4. Oct 2018 — Jan 2019 [monthly]

    Recruiting PHASE2_PHASE3

  5. Jun 2018 — Oct 2018 [monthly]

    Recruiting PHASE2_PHASE3

  6. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

  7. Jan 2017 — Dec 2017 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Oct 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Data source: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations