deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 4-arm NCT02952508

Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia (CLOVER-WaM)

An Open-Label, Multicenter, Phase 2 Study of Iopofosine I 131 (CLR 131) in Patients With Relapsed or Refractory (R/R) Select B-Cell Malignancies (CLOVER-1) and Expansion Cohort in Patients With Waldenstrom Macroglobulinemia (CLOVER-WaM)

Sponsor: Cellectar Biosciences, Inc.

Updated 29 times since 2017 Last updated: Mar 25, 2025 Started: Jul 26, 2017 Primary completion: Dec 22, 2025 Completion: Dec 22, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Central Nervous System Lymphoma and Chronic Lymphocytic Leukemia, this trial is ongoing. The trial is conducted by Cellectar Biosciences, Inc. and has accumulated 29 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Nov 2017 · 2 months · monthly snapshot~Nov 2017 – ~Feb 2018 · 3 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Aug 2019 · 6 months · monthly snapshot~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshot~Sep 2023 – ~Feb 2024 · 5 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Apr 2025 · 6 months · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

29 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Apr 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Oct 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

Show 24 earlier versions
  1. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Sep 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

  3. Feb 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  4. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  5. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  6. Mar 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  7. Jan 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

  8. Nov 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  9. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  10. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  11. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  12. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  13. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  14. May 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  15. Feb 2020 — May 2020 [monthly]

    Recruiting PHASE2

  16. Aug 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  17. Feb 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  18. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  19. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  20. Nov 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

  21. Sep 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  22. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  23. Feb 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE2

  24. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cellectar Biosciences, Inc.
Data source: Cellectar Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .