deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 5-arm NCT02954523

Dasatinib and Osimertinib (AZD9291) in Advanced Non-Small Cell Lung Cancer With EGFR Mutations

Phase I/II Study of Dasatinib and Osimertinib (AZD9291) in Patients With Advanced Non-small Cell Lung Cancer With EGFR Mutations

Sponsor: AstraZeneca

Updated 18 times since 2017 Last updated: Jul 2, 2024 Started: Oct 31, 2016 Primary completion: Aug 31, 2018 Completion: Mar 3, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of accrual

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This PHASE1/PHASE2 trial investigates EGFR Gene Mutation and Nonsmall Cell Lung Cancer and is currently terminated or withdrawn. AstraZeneca leads this study, which shows 18 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~May 2018 · 11 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Mar 2019 · 6 months · monthly snapshot~Mar 2019 – ~Mar 2020 · 12 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Feb 2024 · 24 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1/PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Status: UnknownTerminated

  4. Jul 2024 — Aug 2024 [monthly]

    Unknown PHASE1/PHASE2

    Status: Unknown StatusUnknown · Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. Feb 2024 — Jul 2024 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: Active Not RecruitingUnknown Status

Show 13 earlier versions
  1. Feb 2022 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  6. Mar 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  7. Sep 2018 — Mar 2019 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE1_PHASE2

  9. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1_PHASE2

  10. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  11. Jun 2017 — May 2018 [monthly]

    Recruiting PHASE1_PHASE2

  12. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE1_PHASE2

  13. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Oct 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Bristol-Myers Squibb
  • Chul Kim
  • Hackensack Meridian Health
  • Walter Reed National Military Medical Center
Data source: Georgetown University

For direct contact, visit the study record on ClinicalTrials.gov .