deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02955212

A Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs)

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs)

Sponsor: AbbVie

Updated 24 times since 2017 Last updated: Aug 30, 2021 Started: Jan 3, 2018 Primary completion: Aug 14, 2019 Completion: Sep 3, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02955212, this PHASE3 trial focuses on Rheumatoid Arthritis (RA) and remains completed. Sponsored by AbbVie, it has been updated 24 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Dec 2017 · 7 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Dec 2018 · 2 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Oct 2019 · 3 months · monthly snapshot~Oct 2019 – ~Feb 2020 · 4 months · monthly snapshot~Feb 2020 – ~Sep 2020 · 7 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

24 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Oct 2021 [monthly]

    Completed PHASE3

Show 19 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Sep 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  4. Oct 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  5. Jul 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  7. Dec 2018 — Apr 2019 [monthly]

    Recruiting PHASE3

  8. Oct 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  9. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  10. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  11. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  12. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  13. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  14. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE3

  15. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  16. Dec 2017 — Feb 2018 [monthly]

    Not Yet Recruiting PHASE3

  17. May 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE3

  18. Feb 2017 — May 2017 [monthly]

    Not Yet Recruiting PHASE3

  19. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .