deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT02960854

A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock.

Randomized, Double-Blind, Parallel Group Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936558 (Nivolumab) in Participants With Severe Sepsis or Septic Shock.

Sponsor: Bristol-Myers Squibb

Conditions Severe Sepsis
Interventions Nivolumab
Updated 11 times since 2017 Last updated: Apr 19, 2019 Started: Dec 7, 2016 Primary completion: Jan 5, 2018 Completion: Jan 5, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Severe Sepsis, this trial is completed. The trial is conducted by Bristol-Myers Squibb and has accumulated 11 data snapshots since 2016. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshotRecruiting~Jun 2017 – ~Nov 2017 · 5 months · monthly snapshotRecruiting~Nov 2017 – ~Feb 2018 · 3 months · monthly snapshotActive Not Recruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotCompleted~Jun 2018 – ~May 2019 · 11 months · monthly snapshotCompleted~May 2019 – ~Jan 2021 · 20 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. May 2019 — Jan 2021 [monthly]

    Completed PHASE1

Show 6 earlier versions
  1. Jun 2018 — May 2019 [monthly]

    Completed PHASE1

  2. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  3. Nov 2017 — Feb 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Jun 2017 — Nov 2017 [monthly]

    Recruiting PHASE1

  5. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE1

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
Data source: Bristol-Myers Squibb

For direct contact, visit the study record on ClinicalTrials.gov .