deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT02962895

Safety and Efficacy of VAY736 in Patients With Primary Sjogren's Syndrome (pSS)

Study of Safety and Efficacy of Multiple VAY736 Doses in Patients With Moderate to Severe Primary Sjogren's Syndrome (pSS)

Sponsor: Novartis Pharmaceuticals

Conditions Primary Sjogren Syndrome
Interventions Placebo VAY736
Updated 28 times since 2017 Last updated: Jan 6, 2025 Started: Jun 27, 2017 Primary completion: Jun 30, 2020 Completion: Sep 23, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02962895, this PHASE2 trial focuses on Primary Sjogren Syndrome and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 28 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Dec 2017 · 4 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Dec 2018 · 5 months · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Jul 2019 · 5 months · monthly snapshot~Jul 2019 – ~Mar 2020 · 8 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Feb 2025 · 3 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Feb 2025 — Sep 2025 [monthly]

    Completed PHASE2

  3. Nov 2024 — Feb 2025 [monthly]

    Completed PHASE2

  4. Sep 2024 — Nov 2024 [monthly]

    Completed PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

▶ Show 23 earlier versions

  1. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE2

  2. Feb 2022 — Apr 2022 [monthly]

    Completed PHASE2

  3. Dec 2021 — Feb 2022 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  4. Sep 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  7. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Aug 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Jun 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Apr 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  13. Jul 2019 — Mar 2020 [monthly]

    Recruiting PHASE2

  14. Feb 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  15. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  16. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  17. Jul 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  18. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  19. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  20. Aug 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  21. Jun 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE2

  22. Feb 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE2

  23. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Almada, Portugal , Baltimore, United States , Barcelona, Spain , Berlin, Germany , Birmingham, United Kingdom , Boston, United States , Brasov, Romania , Brest, France , Brussels, Belgium , Budapest, Hungary and 42 more locations