deltatrials
Completed OBSERVATIONAL NCT02966145

4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2 (4RTNI-2)

The Four-Repeat Tauopathy Neuroimaging Initiative

Sponsor: National Institute on Aging (NIA)

Conditions Cortical-basal Ganglionic Degeneration (CBGD) Corticobasal Degeneration (CBD) Corticobasal Syndrome (CBS) Nonfluent Variant Primary Progressive Aphasia (nfvPPA) Oligosymptomatic/Variant Progressive Supranuclear Palsy (o/vPSP) Progressive Supranuclear Palsy (PSP)
Interventions Observational Study
Updated 16 times since 2017 Last updated: Apr 9, 2025 Started: Jan 31, 2016 Primary completion: Feb 28, 2024 Completion: Feb 28, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Cortical-basal Ganglionic Degeneration (CBGD) and Corticobasal Degeneration (CBD) and is currently completed. National Institute on Aging (NIA) leads this study, which shows 16 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshot~Aug 2017 – ~Apr 2018 · 8 months · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Aug 2020 · 22 months · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Dec 2021 · 6 months · monthly snapshot~Dec 2021 – ~Jun 2023 · 18 months · monthly snapshot~Jun 2023 – ~Feb 2024 · 8 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – present · 14 months · monthly snapshot

Change History

16 versions recorded

  1. May 2025 — Present [monthly]

    Completed

    Status: Active Not Recruiting → Completed

  2. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  4. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting

    Status: Unknown Status → Active Not Recruiting

  5. Jun 2023 — Feb 2024 [monthly]

    Unknown Status

    Status: Recruiting → Unknown Status

▶ Show 11 earlier versions

  1. Dec 2021 — Jun 2023 [monthly]

    Recruiting

  2. Jun 2021 — Dec 2021 [monthly]

    Recruiting

  3. Jan 2021 — Jun 2021 [monthly]

    Recruiting

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  5. Aug 2020 — Nov 2020 [monthly]

    Recruiting

  6. Oct 2018 — Aug 2020 [monthly]

    Recruiting

  7. Jun 2018 — Oct 2018 [monthly]

    Recruiting

  8. May 2018 — Jun 2018 [monthly]

    Recruiting

  9. Apr 2018 — May 2018 [monthly]

    Recruiting

    Phase: NA → None

  10. Aug 2017 — Apr 2018 [monthly]

    Recruiting NA

  11. Jan 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

Jan 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute on Aging (NIA)
  • National Institutes of Health (NIH)
  • University of California, San Francisco
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations