deltatrials
Recruiting PHASE1 INTERVENTIONAL 7-arm NCT02966665

: Vascular Function in Health and Disease

Vascular Function in Health & Disease: Rehabilitation for Hypertension; Exercise and Skeletal Muscle Afferent Feedback

Sponsor: Russell Richardson

Conditions Chronic Obstructive Pulmonary Disease Heart Failure Hypertension Pulmonary Artery Hypertension
Interventions Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine Angiotensin-II, Valsartan BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate BQ-123 BQ-123, MitoQ, BH4 Fexofenadine, Ranitidine Maximum Exercise Tests
Updated 14 times since 2017 Last updated: Sep 22, 2025 Started: Sep 30, 2008 Primary completion: Aug 31, 2026 Completion: Aug 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Chronic Obstructive Pulmonary Disease and Heart Failure, this trial is actively recruiting participants. The trial is conducted by Russell Richardson and has accumulated 14 data snapshots since 2008. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshot~Jun 2019 – ~Jun 2020 · 12 months · monthly snapshot~Jun 2020 – ~Oct 2020 · 4 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Nov 2022 · 13 months · monthly snapshot~Nov 2022 – ~Nov 2023 · 12 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Oct 2025 · 10 months · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

14 versions recorded

  1. Oct 2025 — Present [monthly]

    Recruiting PHASE1

  2. Dec 2024 — Oct 2025 [monthly]

    Recruiting PHASE1

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

▶ Show 9 earlier versions

  1. Nov 2022 — Nov 2023 [monthly]

    Recruiting PHASE1

  2. Oct 2021 — Nov 2022 [monthly]

    Recruiting PHASE1

  3. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  4. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  5. Jun 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  6. Jun 2019 — Jun 2020 [monthly]

    Recruiting PHASE1

  7. Jun 2018 — Jun 2019 [monthly]

    Recruiting PHASE1

  8. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Russell Richardson
Data source: University of Utah

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations