deltatrials
Terminated PHASE2 INTERVENTIONAL 8-arm NCT02975336

A Phase II Study of M2951 in SLE

A Phase II, Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study To Evaluate the Safety and Efficacy of M2951 in Subjects With SLE

Sponsor: EMD Serono Research & Development Institute, Inc.

Interventions M2951 Placebo
Updated 27 times since 2017 Last updated: Mar 16, 2021 Started: Jan 4, 2017 Primary completion: Nov 27, 2019 Completion: Mar 23, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study is completed; primary analysis completed.

Listed as NCT02975336, this PHASE2 trial focuses on Systemic Lupus Erythematosus and remains terminated or withdrawn. Sponsored by EMD Serono Research & Development Institute, Inc., it has been updated 27 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jul 2017 · 3 months · monthly snapshot~Jul 2017 – ~Sep 2017 · 2 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Jan 2018 · 3 months · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Dec 2021 · 7 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

27 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. May 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 22 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Terminated PHASE2

  2. Sep 2020 — Jan 2021 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  3. Jun 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  5. Dec 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  6. Oct 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  8. Apr 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  9. Jan 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  10. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  11. Sep 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  12. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  13. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  14. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  15. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE2

  16. Jan 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  17. Oct 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  18. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  19. Jul 2017 — Sep 2017 [monthly]

    Recruiting PHASE2

  20. Apr 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

  21. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  22. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • EMD Serono Research & Development Institute, Inc.
  • Merck KGaA, Darmstadt, Germany
Data source: EMD Serono

For direct contact, visit the study record on ClinicalTrials.gov .