deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT02981082

Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

A Double-blinded, Placebo-controlled Pilot Study of Dimethyl Fumarate (DMF) in Pulmonary Arterial Hypertension (PAH) Associated With Systemic Sclerosis (SSc-PAH): The Effect of DMF on Clinical Disease and Biomarkers of Oxidative Stress.

Sponsor: Biogen

Updated 9 times since 2017 Last updated: Mar 15, 2022 Started: Dec 31, 2016 Primary completion: Feb 10, 2020 Completion: Feb 10, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Low recruitment

This PHASE1 trial investigates Pulmonary; Hypertension and Systemic Sclerosis and is currently terminated or withdrawn. Biogen leads this study, which shows 9 recorded versions since 2016 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshotRecruiting~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshotRecruiting~Mar 2019 – ~May 2020 · 14 months · monthly snapshotRecruiting~May 2020 – ~Jan 2021 · 8 months · monthly snapshotTerminated~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Jan 2021 — Apr 2022 [monthly]

    Terminated PHASE1

  5. May 2020 — Jan 2021 [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

Show 4 earlier versions
  1. Mar 2019 — May 2020 [monthly]

    Recruiting PHASE1

  2. Jan 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  3. Jun 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  4. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biogen
  • Robert Lafyatis
Data source: University of Pittsburgh

For direct contact, visit the study record on ClinicalTrials.gov .