deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT02989662

INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers

Glucocorticoid Antagonists in Heavy Drinkers: Effects on fMRI Connectivity, Withdrawal and Drinking

Sponsor: Johns Hopkins University

Conditions Alcohol Use Disorder
Interventions Mifepristone Placebo - Cap
Updated 17 times since 2017 Last updated: May 29, 2025 Started: Sep 26, 2017 Primary completion: Jan 31, 2024 Completion: Jan 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Alcohol Use Disorder and is currently completed. Johns Hopkins University leads this study, which shows 17 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2019 · 13 months · monthly snapshot~Sep 2019 – ~Sep 2020 · 12 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Feb 2024 · 12 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – present · 14 months · monthly snapshot

Change History

17 versions recorded

  1. Jun 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Jun 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  4. Jun 2024 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Phase: NA → PHASE1_PHASE2

  5. Mar 2024 — Jun 2024 [monthly]

    Completed NA

    Status: Recruiting → Completed

▶ Show 12 earlier versions

  1. Feb 2024 — Mar 2024 [monthly]

    Recruiting NA

  2. Feb 2023 — Feb 2024 [monthly]

    Recruiting NA

  3. Sep 2022 — Feb 2023 [monthly]

    Recruiting NA

  4. Sep 2021 — Sep 2022 [monthly]

    Recruiting NA

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting NA

  6. Sep 2020 — Jan 2021 [monthly]

    Recruiting NA

  7. Sep 2019 — Sep 2020 [monthly]

    Recruiting NA

  8. Aug 2018 — Sep 2019 [monthly]

    Recruiting NA

  9. Jun 2018 — Aug 2018 [monthly]

    Recruiting NA

  10. Jul 2017 — Jun 2018 [monthly]

    Recruiting NA

  11. Feb 2017 — Jul 2017 [monthly]

    Recruiting NA

  12. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Johns Hopkins University
  • National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Data source: Johns Hopkins University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations